Mir Ishraquzzaman

National Heart Foundation Hospital and research Institute, Bangladesh

Abstract Title:

Biography:

Dr. Mir Ishraquzzaman works as a Consultant Cardiologist and the Clinical Deputy Director at the National Heart Foundation Hospital and Research Institute. He earned his MD from Zaporizhzhia Medical University, Ukraine, in 1998, and later did MRCP (UK) in 2014, giving him a strong foundation in cardiovascular medicine. With over 20 years of clinical experience, his primary focus is on hypertension and heart failure management. He is proud to lead the Cardiac Wellness Center, where he runs a comprehensive cardiac rehabilitation program, alongside specialized hypertension (HTN) and heart failure clinics. His approach consistently uses evidence-based practice, preventive strategies, and patient-centered care. Beyond his clinical work, he is actively involved in shaping cardiology standards in Bangladesh. He serves as a member of the Writing Committee for the Hypertension Guideline, helping create national treatment guidelines and protocols. Additionally, he is a Co-Investigator for the National ACS Registry Project, supporting important research on acute coronary syndromes. His commitment to sharing knowledge is reflected in multiple publications in peer-reviewed journals. His main goal is to make sure patients get the best care for their heart health.

Research Interest:

Aims: Little is known regarding clinical outcome of very elderly patients with ST-segment elevation myocardial infarction (STEMI). The aim of this study was to compare clinical outcomes between very elderly patients (aged >85 years) and non-very-elderly patients (aged ≤85 years) with STEMI over a decade.

Methods and Results: The NAMI registry was conducted at a tertiary cardiac care hospital in Bangladesh from January 2015 to December 2024, spanning 10 years. All consecutive STEMI patients admitted to our hospital were included in the study. The clinical outcomes of very elderly and non-very-elderly patients were compared.

A total of 14233 STEMI patients were included in this study, 135 (0.9%) patients were very elderly and 14098 (94.3%) were non-very-elderly. Many of very elderly patients were female (25.9% vs 13.8%; p<0.001). Very elderly patients had significantly more chronic kidney disease (97.0% vs 46.3%; p<0.001). Non-very-elderly patients were predominantly smokers (52.4% vs 34.1%; p<0.001); obese (35.1% vs 20.0%; p<0.001); and diabetic (53.4% vs 40.0%; p=0.002). Regarding CAG, vessel score did not differ significantly. Very-elderly patients received more medical therapy (67.4% vs 37.0%; p<0.001) and non-very-elderly patients received more thrombolytic therapy only (18.5% vs 8.1%; p=0.002) & underwent more pharmaco-invasive therapy (10.9% vs 5.9%; p=0.06), PCI (20.6% vs 9.6%; p=0.002), and primary PCI (13.1% vs 8.9%; p=0.15) than nonvery-elderly patients. Very elderly patients had higher in-hospital complications: acute left ventricular failure (50.4% vs 29.6%; p<0.001); cardiogenic shock (23.0% vs 13.5%; p=0.002); conduction disturbance (18.5% vs 10.0%; p=0.001) arrhythmias (14.1% vs 8.2%; p=0.01) and in-hospital death (11.1% vs 4.1%; p<0.001) than non-very-elderly patients.

Conclusions: Very elderly patients had a higher prevalence of chronic kidney disease, were less likely to undergo invasive therapies, and had worse clinical outcomes.

Key words: Very elderly, STEMI, outcome.